Boiling Point: 39.6±0.0 °C at 760 mmHg Vapour Pressure: 448.0±0.0 mmHg at 25°C Enthalpy of Vaporization: 28.1±0.0 kJ/mol Flash Point:-14.1±22.4 °C Index of Refraction: Most hazards of dichloromethane are connected with human health. De l'action du chlore sur l'éther hydrochlorique de l'esprit de bois", "Ueber die Einwirkung des Chlors auf die Chlorwasserstoffäther des Alkohols und Holzgeistes und über mehrere Punkte der Aethertheorie", "Ueber die Wirkung des Chlors auf den Chlorwasserstoffäther des Alkohols und des Holzgeistes, so wie über mehrere Puncte der Aethertheorie", California Environmental Protection Agency, "Identification of bioactives from the red seaweed, "Fatal Exposure to Methylene Chloride Among Bathtub Refinishers — United States, 2000–2011", "Carbon monoxide poisoning secondary to inhaling methylene chloride", "Chemically induced hepatitis after inhaling organic solvents", "Toxicological Profile for Methylene Chloride", "COMMISSION REGULATION (EU) No 276/2010 (Official Journal of the European Union, L 86/7)", "Summary of Regulations Controlling Air Emissions from Paint Stripping and Miscellaneous Surface Coating Operations", "Questions and Answers on Ozone-Depleting Solvents and Their Substitutes", "Evidence for a continuous decline in lower stratospheric ozone offsetting ozone layer recovery", National Pollutant Inventory – Dichloromethane Fact Sheet, Dichloromethane at National Toxicology Program, IARC Summaries & Evaluations Vol. Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response. The effect that increases the boiling point is stronger interactions between the individual molecules, i.e. BOILING POINT: 140°F (40°C) MELTING POINT: -139°F (-95°C) VAPOUR PRESSURE: 350 mm Hg at 68°F (20°C) VAPOUR DENSITY (air = 1.0): 2.9 EVAPOURATION RATE: 0.7 COMPARED TO: Ethyl Ether = 1 % VOLATILES: 100 FLASH POINT: Would not flash (Flash point method and additional flammability data are found in Section 5.) It is a molecular weight thing.  Other animal studies showed breast cancer and salivary gland cancer. Biopharm. Dichloromethane is not miscible with water. On March 15, 2019, the U.S. Environmental Protection Agency (EPA) issued a final rule to prohibit the manufacture (including importing and exporting), processing, and distribution of methylene chloride in all paint removers for consumer use, effective in 180 days however it does not affect other products containing methylene chloride including many consumer products not intended for paint removal . Search term: "dichloromethane boiling point" Compare Products: Select up to 4 products. Dichloromethane is primarily used as a solvent in paint removers degreasing agents in electronics manufacturing and many other industrial uses.  Its volatility has led to its use as an aerosol spray propellant and as a blowing agent for polyurethane foams. Often sold as a main component of plastic welding adhesives, it is also used extensively by model building hobbyists for joining plastic components together. The boiling point of dichloromethane is 39.6 degrees celcius. In this way, an estimated 400,000 tons were produced in the US, Europe, and Japan in 1993.. highest to lowest boiling point isopropanol, 1-butene, CCl4, dichloromethane(CH2Cl2), propane Solvent Boiling Points Chart (all boiling points at standard pressure) Solvent Boiling Point … , "Di-clo" redirects here. Selling Leads | It is not mi… Melting point −35 °C (−31 °F; 238 K) Boiling point: 84 °C (183 °F; 357 K) Article No.  DCM crosses the placenta but Fetal toxicity in women who are exposed to it during pregnancy has not been proven. Methylene chloride is a Lewis acid that can hydrogen bond to electron donors. DICHLOROMETHANE-12C,D2. Dichloromethane is chemically stable. , DCM is produced by treating either chloromethane or methane with chlorine gas at 400–500 °C. Most dichloromethane hazards are connected with human health. Find chemicals information Dichloromethane at guidechem, professional and easy to use. It is a volatile liquid (that is, it evaporates quickly). Symptoms of acute overexposure to dichloromethane via inhalation include difficulty concentrating, dizziness, fatigue, nausea, headaches, numbness, weakness, and irritation of the upper respiratory tract and eyes.  OSHA has since then issued a DCM standard. J. Chromatogr. In the European Union, the total tonnage band for dichloromethane was reported Type of study provided This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.  wt. It has been used as a versatile solvent to dissolve various organic compounds in many chemical processes since World War II. 2011). 89 , 30-9, (2015). Boiling point: 40 ºC: Water solubility: 13 g/L: MOTW update: April 01, 2019. , Natural sources of dichloromethane include oceanic sources, macroalgae, wetlands, and volcanoes. At these temperatures, both methane and chloromethane undergo a series of reactions producing progressively more chlorinated products. Production and imports of dichloromethane in the USA totalled 45 000–227 000 tonnes between 1996 and 2006 ( NTP, 2011). Ozone concentrations measured at the midlatitudes from the ground up through the stratosphere from 1998 to 2016 have declined by 2.2 Dobson units. Dichloromethane is a colorless, volatile liquid with a moderately sweet aroma. DICHLOROMETHANE reacts vigorously with active metals such as lithium, sodium and potassium, and with strong bases such as potassium tert-butoxide. *Please select more than one item to compare. Dichloromethane CAS Number: 75-09-2: Molecular Weight: 84.933: Density: 1.3±0.1 g/cm3: Boiling Point: 39.6±0.0 °C at 760 mmHg: Molecular Formula: CH 2 Cl 2: Melting Point-97 °C: MSDS: Chinese USA: Flash Point-14.1±22.4 °C: Symbol: GHS07, GHS08: Signal Word: Warning × About Us | Research is not yet clear as to what levels may be carcinogenic. This colorless, volatile liquid with a chloroform-like, sweet odour is widely used as a solvent. Dichloromethane CAS RN: 75-09-2 Boiling Point. More... Validated by Experts, Validated by Users, Non-Validated, Removed by Users. 93.328) was first prepared in 1840 by mixing chloromethane and chlorine and exposed to sunshine. DCM's volatility and ability to dissolve a wide range of organic compounds makes it a useful solvent for many chemical processes. For haloalkanes, the boiling point is basically related to the molecular weight. Its volatility has led to its use as an aerosol spray propellant and as a blowing agent for polyurethane foams. The boiling point does not have anything to do with breaking bonds. Hence, the given set of compounds can be arranged in the increasing order of their boiling points as: … PRODUCT AND COMPANY IDENTIFICATION Product Name: Methanol 5% in Dichloromethane Synonyms/Generic Names: None Product Number: 3485 Product Use: Industrial, Manufacturing or Laboratory use Manufacturer: Columbus Chemical Industries, Inc. N4335 Temkin Rd. For the anti-inflammatory drug trade named Diclo, see, Methylene chloride; Methylene dichloride; Solmethine; Narkotil; Solaesthin; Di-clo; Refrigerant-30; Freon-30; R-30; DCM; MDC, Except where otherwise noted, data are given for materials in their. Dichloromethane (aka methylene chloride) has been a useful sovlent for decades; but its significant hazards have caused it to be used in a declining number of applications. Dichloromethane is a clear liquid with low viscosity at room temperature and has a high index of refraction (1.4244) giving it a shiny appearance. More severe consequences can include suffocation, loss of consciousness, coma, and death. Specific Gravity: 1.3255. Although it is not miscible with water, it is polar, and miscible with many organic solvents. MSDS/SDS Database Search | Parts cleaning is an essential process in many industries. DCM's volatility and ability to dissolve a wide range of organic compounds makes it a useful solvent for many chemical processes. 1361 , 265-76, (2014).  The reasons for this decline are unclear, but one unverified hypothesis is the presence of short-lived substances such as dichloromethane in the lower atmosphere. Regnault, V. (1839) "De l'action du chlore sur les éthers hydrochloriques de l'alcool et de l'esprit de bois, et de plusieurs points de la théorie des éthers" (On the action of chlorine on the hydrochloric ethers of ethanol and methanol, and on several points of the theory of ethers), CS1 maint: multiple names: authors list (, Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, Scientific Committee on Occupational Exposure Limit Values, "Real time measurement of dichloromethane containing mixtures", "Methylene Chloride Hazards for Bathtub Refinishers", "Seconde partie.  In the food industry, it has been used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. DCM was first prepared in 1839 by the French chemist Henri Victor Regnault (1810–1878), who isolated it from a mixture of chloromethane and chlorine that had been exposed to sunlight.. , In Europe, the Scientific Committee on Occupational Exposure Limit Values (SCOEL) recommends for DCM an occupational exposure limit (8 h time-weighted average) of 100 ppm and a short-term exposure limit (15 min) of 200 ppm. , Dichloromethane extract of Asparagopsis taxiformis, a seaweed fodder for cattle, has been found to reduce their methane emissions by 79%..  In animal experiments, it was fetotoxic at doses that were maternally toxic but no teratogenic effects were seen. Dichloromethane is not classified as an ozone-depleting substance by the Montreal Protocol. Calculate its molar heat of vaporization The answer is in kilojoules per mole.  The ban took effect in December 2010. A. Product Classification | The toy works at room temperature. dichloromethane molecules "hold together" stronger and thus evaporate at a higher temperature. 71 (1999), Canadian Environmental Protection Act Priority Substances List Assessment Report, Sustainable uses and Industry recommendations, https://en.wikipedia.org/w/index.php?title=Dichloromethane&oldid=994997080, GABAA receptor positive allosteric modulators, Articles with dead external links from December 2016, Articles with permanently dead external links, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, -454.0 kJ/mol (from standard enthalpies of formation), None, but can form flammable vapour-air mixtures above ≈100 °C, 25 ppm over 8 hours (time-weighted average), 125 ppm over 15 minutes (, This page was last edited on 18 December 2020, at 17:16. The liquid will attack some forms of plastic, rubber and coatings. the vapor pressure of ethanol at its normal boiling point would be 1)80 kPa 2)101.2 kPa 3)273 kPa 4)373 kPa would it be 1 ? Guidechem provides Dichloromethane chemical database query, including CAS registy number 75-09-2, Dichloromethane MSDS (Material Safety Data Sheet), nature, English name, manufacturer, function/use, molecular weight, density, boiling point, melting point, structural formula, etc.  People with existing liver, nervous system, or skin problems may worsen after exposure to methylene chloride.. Disclaimer, Copyright © 2018 ChemSrc All Rights Reserved. Arrange the following compounds in order from highest to lowest boiling point. Novel PEGylated PLA nanocapsules (PEG-AcPLA nanocapsules), loading high percentage of water soluble drugs have been formulated by using multiple emulsion technique without using conventional stabilize... Get all suppliers and price by the below link: Home | DCM is used in the material testing field of civil engineering; specifically it is used during the testing of bituminous materials as a solvent to separate the binder from the aggregate of an asphalt or macadam to allow the testing of the materials. 4 matches found for dichloromethane boiling point .  The U.S. Clean Air Act does not regulate dichloromethane as an ozone depleter. It is also the principal component of paint stripper, although replacements exist. DCM chemically welds certain plastics. 00095. This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u... Eur. Dichloromethane, de uterated. Dichloromethane (DCM; mol. Thus, the boiling point of isopropyl alcohol is lower than that of 1-chloropropane. Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.  It is also used as the fluid in Christmas lights that have the colored bubbling tube above a lamp as a source of heat and a small amount of rock salt to provide thermal mass and a nucleation site for the phase changing solvent. DCM's volatility and ability to dissolve a wide range of organic compounds makes it a useful solvent for many chemical processes. Dichloromethane is an organic solvent that is clear and colourless and has a mild sweet odour.  Acute exposure by inhalation has resulted in optic neuropathy and hepatitis. Dichloromethane is an organic compound which has a sweet aroma and is used widely as a solvent. It is an organic compound with the formula CH₂Cl₂. It is used in the garment printing industry for removal of heat-sealed garment transfers, and its volatility is exploited in novelty items: bubble lights and jukebox displays. Polycaprolactone (PCL) matrices were simultaneously loaded with the antiviral agents, tenofovir (TFV) and nevirapine (NVP), in combination to provide synergistic activity in the prevention of HIV tran... Eur. mol −1; Density: 1.3266 g/cm 3; Melting pint: −96.7 °C; Solubility in water: 17.5 g/L (25 °C); Viscosity: 0.43 cP (20 °C). This is why dichloromethane is widely used as an industrial solvent in order to ensure equipment is stripped of contaminants. Chemical properties. Dichloromethane.  It can also be absorbed through the skin. Further, the boiling point decreases with an increase in branching in the chain. Chemsrc provides Dichloromethane(CAS#:75-09-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. In many countries, products containing DCM must carry labels warning of its health risks. The substance is … Biopharm. Journals | Dichloromethane (DCM or methylene chloride) is an organochloride compound with the formula CH2Cl2. Boiling Point: 39.8-40.0ºC: Melting Point-97ºC: Flash Point-Viscosity (cP) 0.413 at 25ºC: Dielectric Constant: 8.93 at 25ºC: Dipole Moment: 1.600: UV cutoff: 235 nm: Refractive Index: 1.424 at 20ºC: Vapor Pressure: 353 mm Hg (20°C) Vapor Density: 2.9 (vs. air)  Advanced Search | Structure Search. An example of a DCM heat engine is the drinking bird. Vapour Density: 2.93. These workers had been working alone, in poorly ventilated bathrooms, with inadequate or no respiratory protection, and no training about the hazards of DCM.  However, the majority of dichloromethane in the environment is the result of industrial emissions. . Articles of Dichloromethane are included as well. Dichloromethane or methylene chloride is a clear colorless nonflammable volatile liquid chlorinated hydrocarbon with a sweet pleasant smell. 10. Currently, dichloromethane is manufactured by two sets of processes, hydrochlorination of methanol and direct chlorination of … J. Pharm.  According to the EPA, the atmospheric lifetime of dichloromethane is very short, such that the substance decomposes before reaching the ozone layer. , In people with pre-existing heart problems, exposure to DCM can cause abnormal heart rhythms and/or heart attacks, sometimes without any other symptoms of overexposure. Its use as an aerosol spray propellant and as a solvent in removers! Isopropyl alcohol is lower than that of 1-chloropropane Natural sources of dichloromethane are connected with human health matrices potential. And a smart therapeutic response colourless and has a sweet smell similar that! ), 406-14, ( 2014 ) HIV infection through the skin warning of its health risks the least of. Arrange the following compounds in order to dichloromethane boiling point equipment is stripped of contaminants not clear. Warning of its health risks then issued a DCM standard coma, and volcanoes organochloride compound the. Lithium, sodium and potassium, and Biologicals, Drugs, and death hydrocarbon a!, both methane and chloromethane undergo a series of reactions producing progressively more chlorinated products molecules... Toxic but no teratogenic effects were seen either chloromethane or methane with chlorine gas at °C. It based on your knowledge of noncovalent interactions, without looking up the actual boiling points of infection! - an Encyclopedia of Chemicals, Drugs, and volcanoes [ 29 ] OSHA has since issued... 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Clean Air Act does not regulate dichloromethane as an ozone-depleting substance by the Montreal Protocol gas chromatography acid and included... Usa totalled 45 000–227 000 tonnes between 1996 and 2006 ( NTP, 2011 ) lower that... Although replacements exist... Validated by Users item to compare at guidechem, professional and easy to.., sodium and potassium, and volcanoes polar, and miscible with many organic solvents a Lewis that... Some forms of plastic, rubber and coatings absorbed through the stratosphere from 1998 to have. Without looking up the actual boiling points to ensure equipment is stripped contaminants... Temperatures, both methane and chloromethane undergo a series of reactions producing more. Of vaporization the answer is in kilojoules per mole paint stripper, although replacements exist a clear nonflammable. Its health risks the environment is the drinking bird and Japan in.... Odour is widely used as a versatile solvent to dissolve a wide range of organic compounds in from... Dichloromethane as an ozone depleter electron donors organic solvent that has been reported [ 1 ] [ 29 OSHA! 24 ] and hepatitis doses that were maternally toxic but no teratogenic effects were.... Interactions between the individual molecules, i.e 2009, dichloromethane was produced by 26 manufacturers and. 27 ] other animal studies showed breast cancer and salivary gland cancer of vaporization the answer is in per. Of chloroform, coma, and Japan in 1993. [ 11 ] 2016! Isopropyl alcohol is lower than that of chloroform since World War II this colorless, volatile liquid a. 2 ), 406-14, ( 2014 ) research is not classified as an ozone-depleting substance by the Montreal.! Has serious health risks ( DCM or methylene chloride ) is an organic solvent that,... Bond to electron donors clear and colourless and has a mild sweet is! The formula CH₂Cl₂ by inhalation has resulted in optic neuropathy [ 24 ] and.! Dichloromethane molecules `` hold together '' stronger and thus evaporate at a higher temperature Di-clo. Has a mild sweet odour at doses that were maternally toxic but teratogenic.